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Inventors: Green BS, Tzomik I, Arad-Yellin R
Patent Title: Methods and kits for detecting fungal infection
Publication date: 2007
Publication number: WO/2007/057891
Abstract: Methods and kits which utilize a conjugate, preferably an adduct, of ergosterol for determining the presence or level of a broad spectrum of ergosterol-containing organisms (e.g., fungi) in various substrates are disclosed. These methods and kits can be used to accurately and efficiently diagnose a subject having a fungal infection, particularly invasive fungal infection, and to accurately and efficiently detect the presence of fungi and other ergosterol-containing organisms in other substrates. Antibodies and other compounds (e.g., molecularly imprinted polymers) that are capable of selectively binding to ergosterol or to an ergosterol-containing conjugate and methods of producing same are also disclosed.
URL: http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=WO2007057891&F=0
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